As the Biomedical Center in Plzeň explains, the implant essentially acts as a scaffold for new bone cells. The key benefit of biodegradable implants in biomedicine is that, unlike previously used materials like metals, they allow the patient's own bone cells to grow into them, ultimately transforming into new bone tissue. Due to the low temperature, it retains its bioactivity, meaning it doesn't lose the ability to influence living tissue. This paste is then used to print the implant at a temperature not exceeding 37☌, and it hardens in strength within a few hours in an incubator. Her task involves synthesizing these components and preparing a paste for 3D printing. "We also enrich these materials with additional substances, such as pro-healing compounds, antibacterial proteins, or growth factors," adds Klára Lysáková, who focuses on hydrogel and cement materials for targeted regenerative medicine as part of her doctoral studies. Lucy Vojtová, who leads the Advanced Biomaterials group at CEITEC Brno University of Technology and is also the project leader of PROFiBONE, explains that the ceramic component is a special type of calcium-based bone mineral found in our bones.
This ink consists of a liquid hydrogel component containing a special biodegradable polymer dissolved in water and a powder component of ceramic and cement. These implants are 3D-printed using a special bone ink developed as part of the project.
They use this material to 3D-print implants that can be precisely customized to fit the patient's size and shape of the bone defect while incorporating necessary bioactive substances.Īt CEITEC Brno University of Technology, professional bone implants are being developed that can be tailored to both the size and shape of the bone defect and its biological requirements. This groundbreaking material is being developed by scientists from CEITEC Brno University of Technology in collaboration with the Faculty of Medicine in Plzeň at Charles University and Icelandic partners. The Czech-Icelandic project PROFiBONE presents innovative 3D-printed bone implants designed to meet the specific needs of patients and promote bone healing. Text shared by permission of the author (EEA and Norway Grants).
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